Adaptive immunity-dependent intestinal hypermotility contributes to host defense against Giardia spp.
نویسندگان
چکیده
Humans infected with Giardia exhibit intestinal hypermotility, but the underlying mechanisms and functional significance are uncertain. Here we show in murine models of giardiasis that small-intestinal hypermotility occurs in a delayed fashion relative to peak parasite burden, is dependent on adaptive immune defenses, and contributes to giardial clearance.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 74 4 شماره
صفحات -
تاریخ انتشار 2006